Seek and (Don’t) Destroy

UC Berkeley research strives to understand the cell’s complex recycling program and how we can use it to treat diseases.

In 2020, I was chosen to participate in the Science Writing for the Public workshop through Berkeley QB3. (You can read works written by other workshop participants here.) There is a lot of research at UC Berkeley on the biology of the ubiquitin-proteasome system and its role in cellular recycling, so I thought for my workshop article I could write (and illustrate) a piece giving a state of the field perspective.

Protein recycling by the ubiquitin-proteasome system.

PROTAC: Harnessing the UPS for therapeutic targeted protein degradation.

DUBTAC: Targeted protein stabilization provides an additional therapeutic modality.

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Macromolecular Wonders of the Cell